Corel Pharma Chem

Kyron T-314

Kyron T-314 is derived from crosslinked polymer of Polycarboxylic acids as per USP/NF & has the K+ ionic form. It is a very high purity polymer used in pharmaceutical formulations as a super fast disintegrant as well as dissolution improver in solid dosage forms like tablets, capsules, pellets etc. It is available in white free flowing powder hence it is suitable for the both wet granulation as well as direct compression system for tablet formulations.

Application
Advantages
Others

As Disintegrating agent: Kyron T-314 has a very high swelling tendency of hydration either in contact with water or G.I. fluids causing fast disintegration without the formation of lumps and thus acts as an effective tablet super disintegrant. Required quantity is from 0.5% to 4.0% to get fast disintegration.

As Dissolution Improver: Kyron T-314 breaks the tablets into very smaller particles, thus it increases the effective surface area for the absorption of the active substances and thus it increases the dissolution and bioavailability of the active substances. Required quantity is from 2.0% to 6.0% for dissolution improvement.

  • Rapid disintegrating agent
  • Elimination of lump formation
  • Compatible with all therapeutic agents and excipients
  • Imparts excellent strength to the tablets
  • Elimination of the sticking problems to the dies and punch
  • Improves bioavailability of the drug
  • Uniformly mix with low dose tablets blend or formulations
  • Smooth surface after storage
  • Provide smooth cream-like mouth feel, so more suitable for ODT
  • Suitable for both direct compression and wet granulation methods
  • Cost effective
  • White in color
  • Directly compressible grade
  • Dissolution improver
  • Effective at very low concentration (0.5 to 4.0%).

Toxicity

Kyron T-314 is high molecular weight polymer, so doesn't get absorbed by body tissue and is safe for human consumption. It has no physiological action at recommended dosage and it is non toxic.

Storage

Store in tightly closed container. Keep away from moisture. If moisture is absorbed then dry at 90C to 100C to remove moisture content and make it below 10%.

Packing

5 kg, 10 kg, 20 kg, net in laminated corrugated box with polyethylene liner.

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