Corel Pharma Chem

ACRYCOAT

ACRYCOAT range is transparent or colored film forming coating polymers based on methacrylic acid co-polymers type A, B & C confirms to USP/NF & EP specifications. The range of Acrycoat is useful for film coating, enteric coating, moisture barrier coating, sustained release, taste masking of bitter drugs, binder for powders, transdermal therapeutic system etc.

Grade
Advantages
Others
Application Grade* Use Level** Pharmacopeial Monographs Advantages
Enteric Coating (Drug delivery in Jejunum) Acrycoat L100 4.0-5.0% • USP/NF: Methacrylic Acid Copolymer, Type A - NF

• Ph.Eur.: Methacrylic Acid - Methyl Methacrylate Copolymer (1:1) Type A
• Organic / solvent  coating system

• Less quantity requirement
Acrycoat L 12.5
Enteric Coating (Drug delivery in duodenum) Acrycoat L100D 4.0-5.0% • USP/NF: Methacrylic Acid Copolymer, Type C - NF 

• Ph.Eur.: Methacrylic Acid - Ethyl  Acrylate Copolymer (1:1) Type A
• Aqueous & semi aqueous coating system

• Less quantity requirement
Acrycoat L30D
Taste masking Acrycoat EPO 0.5 - 0.7% • USP/NF: Amino Methacrylate Copolymer - NF

• Ph.Eur.: Basic Butylated Methacrylate Copolymer 
• Rapidly disintegrating film in acidic media

• Less quantity required

• Low water vapor permeability  
Moisture barrier Acrycoat E100
Film coating  Acrycoat E100-40
Tablet binder Acrycoat E12.5
Film coating Acrycoat E 30 D 0.5 - 0.7% • USP/NF: Ethyl Acrylate & Methyl Methacrylate Copolymer Dispersion - NF

• Ph.Eur.: Polyacrylate Dispersion 30%
• No plasticizer is required 

• Highly Flexible film

• Low permeability film

• Suitable for matrix 
Sustained Release  Acrycoat E 30 D 10.0 - 20.0%
Sustained release (Insoluble & High Permeability) Acrycoat RLPO 10.0 - 20.0% • USP/NF: Ammonia Methacrylate Copolymer, Type A - NF

• Ph.Eur.: Ammonia Methacrylate Copolymer, Type A
• pH independent polymer

• Suitable for matrix

• Time controlled release
Acrycoat RL30 D
Acrycoat RL100
Sustained release (Insoluble & Low  Permeability) Acrycoat RSPO • USP/NF: Ammonia Methacrylate Copolymer, Type B - NF

• Ph.Eur.: Ammonia Methacrylate  Copolymer, Type B
Acrycoat RS30D
Acrycoat RS100
Sustained release  Acrycoat S100 10.0 - 20.0% • USP/NF: Methacrylic Acid Copolymer, Type B - NF

• Ph Eur.: Methacrylic Acid - Methyl Methacrylate Copolymer (1:2)
• pH dependent polymer 

• Mixing possibility with Acrycoat L100
Enteric coating (Drug delivery in Colon) Acrycoat S12.5
Acrycoat FS 30D • Acrylate Copolymer • pH independent polymer

• Mixing possibility with Acrycoat L-30 D

* Plasticizer needed (where the films are brittle, to improve film elasiticity)
Recommended Plasticizers - Triethyl Citrate, Castor Oil, Propylene glycol, Polyethylene glycol, Di butyl phtalate, Triacetin, Dibutyl sebacate etc.

**Depends upon facilities available at customer premises like type of product, batch size, equipments etc.

  • Option of solvent, semi aqueous and aqueous vehicle.
  • Less quantity required so reducing volume of coating solution thus shorting production time.
  • Stability over a broad temperature range.
  • Exhibits excellent color value.
  • Cost effective.
  • Easy to formulate.

Toxicity

As Acrycoat range is a high molecular weight polymer, it cannot be absorbed by body. Thus, it is safe for human consumption.

Test for toxicological tolerance shows that it does not have any pronounced or physiological action.

Storage

Powder: Store at a dry place, below 40°C.

Liquid: Store at a dry place, between 5°C to 35°C. Do not freeze.

Self Life

Powder form: Five years from date of manufacturing in intact condition.

Liquid form: Two year from date of manufacturing in intact condition.

Packing

Powder form: 5kg and 20kg net in corrugated with polyethylene liner.

Liquid form: 20kg plastic carboys & 50kg plastic drum.

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